Cynthia Chappell, Pflag Houston Voices

“A Biological Explanation for Human Orientation” DVD

Presented at Reconciling Hearts Forum     November 12, 2006

 

Cynthia is a Pflag Mom.  Her oldest son came out to their family when he was thirty years old.  Seven years later Cynthia, a scientist herself, has explored the research about homosexuality to inform herself.  She found the information to be hard to access for the general public and so decided to present the information in a more accessible format.  Thus, her lectures and this DVD.  In the DVD she attempts to present            

            1.  Fundamental biological concepts

            2.  The latest and best evidence from studies of good scientific design that have been replicated

            3.  The influence of such research on human populations

 

Biological diversity has made human beings successful.  Factors of height, weight, blood pressure, immune response, etc. are what keep humans robust.  All of these factors follow a normal distribution which appears as a bell curve on a graph.  Sexual orientation is another factor like these with heterosexuals being the majority and the minority (the tails) being about 4-5% exclusively gay males and 2-4% exclusively lesbians.

 

Scientific studies are based on population-based evidence, on groups rather than on particular individuals.  One case on one person cannot prove or disprove a generalization.  Associations for characteristics in a population must be statistically significant.  An example is “smoking.”  We know that smoking is dangerous to your health and causes cancer, but small numbers in the population don’t get cancer when they smoke and other small numbers get cancer and have never smoked.  The exceptions don’t disprove the generalization.

 

It is difficult to set up a study design without having some deficiencies.  With regard to studies of homosexuality, it is difficult to accurately define what a “homosexual” is because data is reported by persons who have different knowledge themselves based on cultural differences and fear of revealing themselves. The populations are therefore, not “clean”.  An example of cultural differences is that in Spain, only the recipient in a sexual relationship is considered the homosexual, not both persons.

 

People question whether homosexuality is primarily biological or psychosocial. One study helps answer the question. Thirty-nine genetic males (XY) who were born with poorly differentiated genitalia were followed until adulthood after they were surgically reassigned and raised as females.  This means that they received all of the cultural expectations for being female.  As adults they were asked how they identified sexually; 69% identified as males; 7% as females; and 24% refused or couldn’t answer.  This study certainly points to a genetic influence.

 

Many family, or pedigree studies, tend in the same direction. In families of a gay person, there are increased rates of homosexuality in maternal male relatives; 5-25% of sisters of lesbians are lesbian; 9-22% of brothers of gays are gay also, all much higher incidences than in families of straight persons.  There is some co-incidence with opposite sex siblings which is statistically significant as well.  Six studies of identical twins show a 52% likelihood of sharing the same homosexual orientation whereas with fraternal twins the likelihood is 22%.  Gay men also have more older brothers who are gay, although there is no association between gay men and older sisters.  When the age of the parents is controlled there are no associations. 

 

Some have asked, “Is there a gay gene”?  There is no one gene responsible for sexual orientation. There are at least 51 genes responsible for sexual development with seven showing the greatest effect. However, in linkage studies (molecular), there is a 66-67% genetic linkage between gay brothers and 58% between lesbian sisters.  A brother of a gay man has a 9-22% chance of being gay, while in the general population the incidence is 4-5%.  A sister of a lesbian has a 5-25% chance of being lesbian also while in the general population the incidence is 2-4%.  There is obviously something genetic going on.

 

Research seems to suggest that although sex, maleness or femaleness, is established at conception, actual sex differentiation seems to occur between the 8-16 week of gestation.  It appears that fetal hormones present during that time act on all body tissues giving rise to male or female characteristics.  The presence or absence of certain androgens can result in either feminization or masculization of a biologically male or female.  For example, sometimes genetic males are born with feminization of testes and are often reassigned by physicians to females because their organs look female.  In a study following such cases 93% of these persons expressed attraction to men.  Similarly, genetic females with masculization who were surgically altered to male traits expressed a 70% attraction to females.

 

Additionally, there have been brain studies and examination of a multitude of characteristics that show associations between “gayness” and certain physical characteristics. The upshot of most current studies is that the genetic component is extremely significant.  If a biological cause is apparent, it is evident that homosexuality is a normal variant of human sexuality, about which a person does not have a choice. Nor should the person have to choose.

 

With the increased prevalence of anti-discrimination laws and exposure of variations in sexuality through the media, openness on the subject of human sexuality seems more possible than it was just a few years ago.  It is clear that expecting persons to change something about themselves over which they have no causal control is counterproductive.

 

(These notes do not communicate all of the essence of the DVD.  So the notes are somewhat inadequate. However, we hope that for those who are interested in “cause” this might help.)